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Research Project Description

Nanotechnology Fellowship
Office of Regulatory Affairs
Arkansas Regional Laboratory
U.S. Food and Drug Administration
Jefferson, AR


Project Description:

A fellowship opportunity is currently available with the Office of Regulatory Affairs (ORA) at the Arkansas Regional Laboratory of the U.S. Food and Drug Administration (FDA). The selected participant will be located at the Nanotechnology Core Facility, which was developed to support the technical needs of scientists involved in determining the toxicity, safety, and characterization of nanomaterials.

Under the guidance of a mentor, the selected participant will collaborate with multi-disciplinary research efforts within the National Center for Toxicological Research (NCTR)/ORA Nanotechnology Core Facility. Opportunities may include:

  • Applying x-ray fluorescence (XRF) spectroscopy as a screening tool for nanoscale materials in FDA regulated products
  • Developing regulatory methods for the characterization of nanoscale metal oxides in sunscreens, dietary supplements, and feminine hygiene products
  • Developing and applying liquid chromatography/mass spectrometry techniques for the characterization and identification of liposomal nanoparticles within FDA regulated products
  • Developing hyphenated size-based separation techniques (e.g., asymmetric field flow fractionation, capillary electrophoresis, liquid chromatography) using inductively coupled plasma/mass spectrometry (ICP/MS)
  • Developing methods to detect toxic elements in nano-based dietary supplements using ICP/MS

The following analytical techniques will be used to support these research activities: ICP/MS, asymmetric field flow fractionation (AFFF), x-ray diffraction (XRD), particle size analysis (multiple methods including dynamic light scattering, photon cross correlation spectroscopy, and particle tracking analysis), spectroscopy (FTIR, UV/VIS, fluorescence, XRF, Raman), atomic force microscopy (AFM), high resolution mass spectrometry (HRMS), and electron microscopy with elemental analysis capabilities.

This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend commensurate with education level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at ORA in the Jefferson, Arkansas, area. Participants do not become employees of FDA or the program administrator, and there are no fringe benefits paid.


  • A Doctoral degree in chemistry, materials science, microbiology, or physics with an emphasis in nanotechnology within the last five years.
  • Experience in the characterization of nanomaterials using spectroscopy, microscopy, or other current published methodologies is preferred.

Technical Questions:

Sean W. Linder, Ph.D.
Office of Regulatory Affairs/Arkansas Regional Laboratory
U.S. Food and Drug Administration
Jefferson, Arkansas 72079
Tel: 870-543-4667

How to Apply:

To be considered, please send a current CV/resume to the attention of Please reference FDA-ORA-2014-0050 in all communication.